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Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications.
Rifai, Aaqil; Tran, Nhiem; Lau, Desmond W; Elbourne, Aaron; Zhan, Hualin; Stacey, Alastair D; Mayes, Edwin L H; Sarker, Avik; Ivanova, Elena P; Crawford, Russell J; Tran, Phong A; Gibson, Brant C; Greentree, Andrew D; Pirogova, Elena; Fox, Kate.
Afiliación
  • Zhan H; School of Physics , University of Melbourne , Parkville , Victoria 3010 , Australia.
  • Stacey AD; School of Physics , University of Melbourne , Parkville , Victoria 3010 , Australia.
  • Mayes ELH; RMIT Microscopy and Microanalysis Facility (RMMF) , RMIT University , Melbourne , Victoria 3001 , Australia.
  • Ivanova EP; School of Science , Swinburne University of Technology , Hawthorn , Victoria 3122 , Australia.
  • Tran PA; Institute of Health and Biomedical Innovation , Queensland University of Technology , Kelvin Grove , Queensland 4059 , Australia.
ACS Appl Mater Interfaces ; 10(10): 8474-8484, 2018 Mar 14.
Article en En | MEDLINE | ID: mdl-29470044
Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Titanio Límite: Animals Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Titanio Límite: Animals Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos