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Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children.
Nicol, Mark P; Workman, Lesley; Prins, Margaretha; Bateman, Lindy; Ghebrekristos, Yonas; Mbhele, Silindile; Denkinger, Claudia M; Zar, Heather J.
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  • Nicol MP; From the Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, National Health Laboratory Service.
  • Workman L; Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
  • Prins M; Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
  • Bateman L; Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
  • Ghebrekristos Y; From the Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, National Health Laboratory Service.
  • Mbhele S; From the Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, National Health Laboratory Service.
  • Denkinger CM; FIND (Foundation for Innovative New Diagnostics), Geneva, Switzerland.
  • Zar HJ; Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
Pediatr Infect Dis J ; 37(10): e261-e263, 2018 10.
Article en En | MEDLINE | ID: mdl-29474257
ABSTRACT
We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esputo / Tuberculosis Pulmonar / Técnicas de Diagnóstico Molecular Tipo de estudio: Diagnostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: Pediatr Infect Dis J Asunto de la revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esputo / Tuberculosis Pulmonar / Técnicas de Diagnóstico Molecular Tipo de estudio: Diagnostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: Pediatr Infect Dis J Asunto de la revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Año: 2018 Tipo del documento: Article