Non-invasive assessment of coronary artery geometry using coronary CTA.
J Cardiovasc Comput Tomogr
; 12(3): 257-260, 2018.
Article
en En
| MEDLINE
| ID: mdl-29486988
ABSTRACT
AIM:
To assess the association of coronary artery geometry with the severity of coronary artery disease (CAD).METHODS:
73 asymptomatic individuals at increased risk of CAD due to peripheral vascular disease (18 women, mean age 63.5⯱â¯8.2 years) underwent coronary computed tomography angiography (coronary CTA) using first generation dual-source CT. Curvature and tortuosity of the coronary arteries were quantified using semi-automatically generated centerlines. Measurements were performed for individual segments and for the entire artery. Coronary segments were labeled according to the presence of significant stenosis, defined as >70% luminal narrowing, and the presence of plaque. Comparisons were made by segment and by artery, using linear mixed models.RESULTS:
Overall, median curvature and tortuosity were, respectively, 0.094 [0.071; 0.120] and 1.080 [1.040; 1.120] on a per-segment level, and 0.096 [0.078; 0.118] and 1.175 [1.090; 1.420] on a per-artery level. Curvature was associated with significant stenosis at a per-segment (pâ¯<â¯0.001) and per-artery level (pâ¯=â¯0.002). Curvature was 16.7% higher for segments with stenosis, and 13.8% higher for arteries with stenosis. Tortuosity was associated with significant stenosis only at the per-segment level (pâ¯=â¯0.002). Curvature was related to the presence of plaque at the per-segment (pâ¯<â¯0.001) and per-artery level (pâ¯<â¯0.001), tortuosity was only related to plaque at the per-segment level (pâ¯<â¯0.001).CONCLUSION:
Coronary artery geometry as derived from coronary CTA is related to the presence of plaque and significant stenosis.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de la Arteria Coronaria
/
Angiografía Coronaria
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Vasos Coronarios
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Estenosis Coronaria
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Angiografía por Tomografía Computarizada
Tipo de estudio:
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Cardiovasc Comput Tomogr
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
/
RADIOLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Países Bajos