Activity-Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential &#945;-Globin-Modulating Deubiquitinase.

Meledin, Roman; Mali, Sachitanand M; Kleifeld, Oded; Brik, Ashraf

Activity-Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α-Globin-Modulating Deubiquitinase.

Meledin, Roman; Mali, Sachitanand M; Kleifeld, Oded; Brik, Ashraf.

Afiliación

Meledin R; Schulich Faculty of Chemistry, Technion Israel Institute of Technology, Haifa, 3200008, Israel.
Mali SM; Schulich Faculty of Chemistry, Technion Israel Institute of Technology, Haifa, 3200008, Israel.
Kleifeld O; Faculty of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel.
Brik A; Schulich Faculty of Chemistry, Technion Israel Institute of Technology, Haifa, 3200008, Israel.

Angew Chem Int Ed Engl ; 57(20): 5645-5649, 2018 05 14.

Article en En | MEDLINE | ID: mdl-29527788

Asunto(s)

Alanina/análogos & derivados; Enzimas Desubicuitinizantes/metabolismo; Sondas Moleculares/metabolismo; Globinas alfa/metabolismo; Alanina/biosíntesis; Alanina/química; Enzimas Desubicuitinizantes/química; Humanos; Sondas Moleculares/química; Estructura Molecular; Globinas alfa/química

Palabras clave

activity-based probes; chemical proteomics; dehydroalanine; protein modifications; ubiquitin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sondas Moleculares / Alanina / Globinas alfa / Enzimas Desubicuitinizantes Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2018 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Alemania

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