[Clinical and pathological characteristics of intravascular lymphomas]. / Klinische und pathologische Charakteristika intravaskulärer Lymphome.
Pathologe
; 39(3): 242-248, 2018 May.
Article
en De
| MEDLINE
| ID: mdl-29541829
ABSTRACT
Intravascular Bcell lymphomas (IVL) are rare neoplasms that can manifest at any age (mean age ~62-63 years). About half of the cases are associated with Epstein-Barr virus. The most common sites of manifestation are the brain, skin, and bone marrow. The diagnosis is difficult due to unspecific clinical presentation and laboratory changes. FACS (fluorescence-activated cell sorting) and clonality analysis from peripheral blood and radiological findings are often not diagnostic. The most sensitive and most specific diagnostic method is the histopathological and immunohistochemical evaluation of a tissue biopsy. Because of the rarity of this disease, little is known about therapy and prognosis, whereby therapy is mainly similar to non-IVL lymphomas. The prognosis is poor; median survival after diagnosis is approximately one year.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Vasculares
/
Linfoma
Tipo de estudio:
Prognostic_studies
Límite:
Humans
/
Middle aged
Idioma:
De
Revista:
Pathologe
Año:
2018
Tipo del documento:
Article