Calcium carbonate-methylene blue nanohybrids for photodynamic therapy and ultrasound imaging.
Sci China Life Sci
; 61(4): 483-491, 2018 04.
Article
en En
| MEDLINE
| ID: mdl-29546670
ABSTRACT
Photodynamic therapy plays an important role in cancer treatment. In this work, methylene blue (MB)-embedded calcium carbonate nanorods (CaCO3-MB NRs) have been synthesized for pH-responsive photodynamic therapy and ultrasound imaging. The morphology of CaCO3-MB NRs can be controlled by modulating the concentration of Na2CO3 aqueous solution. The generation of effective reactive oxygen species (ROS) were confirmed by 1,3-diphenylisobenzofuran (DPBF) probe. Both photodynamic therapy performance and echogenic performance of CaCO3-MB NRs were investigated to confirm the feasibility of CaCO3-MB nanohybrids for ultrasound image-guided photodynamic therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
Carbonato de Calcio
/
Ultrasonografía
/
Nanoestructuras
/
Nanomedicina Teranóstica
/
Azul de Metileno
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Sci China Life Sci
Asunto de la revista:
BIOLOGIA
/
CIENCIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
China