Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTP&#963; receptors promotes a beneficial inflammatory response following spinal cord injury.

Dyck, Scott; Kataria, Hardeep; Alizadeh, Arsalan; Santhosh, Kallivalappil T; Lang, Bradley; Silver, Jerry; Karimi-Abdolrezaee, Soheila

Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury.

Dyck, Scott; Kataria, Hardeep; Alizadeh, Arsalan; Santhosh, Kallivalappil T; Lang, Bradley; Silver, Jerry; Karimi-Abdolrezaee, Soheila.

Afiliación

Dyck S; Department of Physiology and Pathophysiology, the Regenerative Medicine Program, the Spinal Cord Research Center, University of Manitoba, 629-Basic Medical Sciences Building, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada.
Kataria H; Department of Physiology and Pathophysiology, the Regenerative Medicine Program, the Spinal Cord Research Center, University of Manitoba, 629-Basic Medical Sciences Building, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada.
Alizadeh A; Department of Physiology and Pathophysiology, the Regenerative Medicine Program, the Spinal Cord Research Center, University of Manitoba, 629-Basic Medical Sciences Building, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada.
Santhosh KT; Department of Physiology and Pathophysiology, the Regenerative Medicine Program, the Spinal Cord Research Center, University of Manitoba, 629-Basic Medical Sciences Building, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada.
Lang B; Department of Neuroscience, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Silver J; Department of Neuroscience, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Karimi-Abdolrezaee S; Department of Physiology and Pathophysiology, the Regenerative Medicine Program, the Spinal Cord Research Center, University of Manitoba, 629-Basic Medical Sciences Building, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada. Soheila.Karimi@umanitoba.ca.

J Neuroinflammation ; 15(1): 90, 2018 Mar 20.

Article en En | MEDLINE | ID: mdl-29558941

Asunto(s)

Proteoglicanos Tipo Condroitín Sulfato/metabolismo; Inflamación/etiología; Inflamación/metabolismo; Proteína Tirosina Fosfatasa no Receptora Tipo 11/metabolismo; Proteínas Tirosina Fosfatasas Clase 2 Similares a Receptores/metabolismo; Traumatismos de la Médula Espinal/complicaciones; Animales; Animales Recién Nacidos; Movimiento Celular/efectos de los fármacos; Polaridad Celular/efectos de los fármacos; Células Cultivadas; Medios de Cultivo Condicionados/farmacología; Citocinas/metabolismo; Citocinas/farmacología; Modelos Animales de Enfermedad; Inhibidores Enzimáticos/farmacología; Femenino; Regulación de la Expresión Génica/fisiología; Microglía/efectos de los fármacos; Microglía/metabolismo; Células-Madre Neurales/efectos de los fármacos; Peroxidasa/metabolismo; Fagocitosis/efectos de los fármacos; Ratas; Ratas Sprague-Dawley

Palabras clave

Chondroitin sulfate proteoglycans; Leukocyte common antigen-related receptor; Microglia; Neural precursor cells; Neuroinflammation; Protein tyrosine phosphatase sigma receptor; Spinal cord injury

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoglicanos Tipo Condroitín Sulfato / Traumatismos de la Médula Espinal / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Proteínas Tirosina Fosfatasas Clase 2 Similares a Receptores / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido

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