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Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aß42, Tau, TREM2, and TYROBP in Drosophila models.
Sekiya, Michiko; Wang, Minghui; Fujisaki, Naoki; Sakakibara, Yasufumi; Quan, Xiuming; Ehrlich, Michelle E; De Jager, Philip L; Bennett, David A; Schadt, Eric E; Gandy, Sam; Ando, Kanae; Zhang, Bin; Iijima, Koichi M.
Afiliación
  • Sekiya M; Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.
  • Wang M; Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, Room 8-111, Box 1498, New York, NY, 10029, USA.
  • Fujisaki N; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
  • Sakakibara Y; Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.
  • Quan X; Department of Experimental Gerontology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Japan.
  • Ehrlich ME; Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.
  • De Jager PL; Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.
  • Bennett DA; Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, Room 8-111, Box 1498, New York, NY, 10029, USA.
  • Schadt EE; Department of Neurology, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gandy S; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ando K; Center for translational & Computational Neuroimmunology, Department of Neurology, The Neurological Institute of New York, Columbia University Medical Center, New York, NY, USA.
  • Zhang B; Broad Institute, Cambridge, MA, USA.
  • Iijima KM; Rush Alzheimer's Disease Research Center and Department of Neurology, Rush University Medical Center, 1750 W. Congress Parkway, Chicago, IL, 60612, USA.
Genome Med ; 10(1): 26, 2018 03 29.
Article en En | MEDLINE | ID: mdl-29598827
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Receptores Inmunológicos / Péptidos beta-Amiloides / Proteínas tau / Proteínas de Drosophila / Proteínas Adaptadoras Transductoras de Señales / Drosophila melanogaster / Enfermedad de Alzheimer / Proteínas de la Membrana Límite: Animals / Female / Humans / Male Idioma: En Revista: Genome Med Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Receptores Inmunológicos / Péptidos beta-Amiloides / Proteínas tau / Proteínas de Drosophila / Proteínas Adaptadoras Transductoras de Señales / Drosophila melanogaster / Enfermedad de Alzheimer / Proteínas de la Membrana Límite: Animals / Female / Humans / Male Idioma: En Revista: Genome Med Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido