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Blood Lead Levels of Children in Flint, Michigan: 2006-2016.
Gómez, Hernán F; Borgialli, Dominic A; Sharman, Mahesh; Shah, Keneil K; Scolpino, Anthony J; Oleske, James M; Bogden, John D.
Afiliación
  • Gómez HF; Department of Emergency Medicine, Medical Toxicology, University of Michigan, Ann Arbor, Division of Pediatric Emergency Medicine, Hurley Medical Center, Flint, MI; Division of Pediatric Emergency Medicine, Hurley Medical Center, Flint, MI. Electronic address: hfgx@umich.edu.
  • Borgialli DA; Division of Pediatric Emergency Medicine, Hurley Medical Center, Flint, MI; Department of Emergency Medicine, University of Michigan, Ann Arbor, Flint, MI.
  • Sharman M; Department of Pediatrics, Michigan State University College of Human Medicine, Hurley Medical Center, Flint, MI.
  • Shah KK; Rutgers New Jersey Medical School, Newark, NJ.
  • Scolpino AJ; Department of Pediatrics, Rutgers New Jersey Medical School, Newark, NJ.
  • Oleske JM; Department of Pediatrics, Rutgers New Jersey Medical School, Newark, NJ.
  • Bogden JD; Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ.
J Pediatr ; 197: 158-164, 2018 06.
Article en En | MEDLINE | ID: mdl-29599069
ABSTRACT

OBJECTIVE:

We evaluated the increases in blood lead levels (BLLs) observed in young children in Flint, Michigan, during their exposure to corrosive Flint River water during the years 2014 and 2015 and compared their BLLs to those of Flint children measured during the years 2006-2013 and 2016. STUDY

DESIGN:

This was a retrospective study design using BLLs extracted from databases from 2006 to 2016. We analyzed a population sample of 15 817 BLLs from children aged ≤5 years with potential exposure to contaminated Flint River water. Percentages of BLLs ≥5.0 µg/dL and geometric mean (GM) BLLs were analyzed over time.

RESULTS:

A significant decline in the percentages of BLLs ≥5.0 µg/dL from 11.8% in 2006 to 3.2% in 2016 was observed (P < .001). GM ± SE BLLs decreased from 2.33 ± 0.04 µg/dL in 2006 to 1.15 ± 0.02 µg/dL in 2016 (P < .001). GM BLLs increased twice from 1.75 ± 0.03 µg/dL to 1.87 ± 0.03 µg/dL (2010-2011) and from 1.19 ± 0.02 µg/dL to 1.30 ± 0.02 µg/dL (2014-2015). Overall, from 2006 to 2016, there was a 72.9% decrease in the percentage of children with BLLs ≥5.0 µg/dL and a 50.6% decrease in GM BLLs.

CONCLUSION:

These findings suggest that the 11 year trend of annual decreases in BLLs in children in Flint, Michigan, reversed to a degree consistent with random variation from 2010 to 2011, and again during the exposure to Flint River water in 2014-2015. Historically, public health efforts to reduce BLLs of young children in Flint have been effective over the 11-year period studied.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación Química del Agua / Exposición a Riesgos Ambientales / Plomo / Intoxicación por Plomo Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: J Pediatr Año: 2018 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación Química del Agua / Exposición a Riesgos Ambientales / Plomo / Intoxicación por Plomo Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: J Pediatr Año: 2018 Tipo del documento: Article
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