pyNBS: a Python implementation for network-based stratification of tumor mutations.
Bioinformatics
; 34(16): 2859-2861, 2018 08 15.
Article
en En
| MEDLINE
| ID: mdl-29608663
ABSTRACT
Summary:
We present pyNBS a modularized Python 2.7 implementation of the network-based stratification (NBS) algorithm for stratifying tumor somatic mutation profiles into molecularly and clinically relevant subtypes. In addition to release of the software, we benchmark its key parameters and provide a compact cancer reference network that increases the significance of tumor stratification using the NBS algorithm. The structure of the code exposes key steps of the algorithm to foster further collaborative development. Availability and implementation The package, along with examples and data, can be downloaded and installed from the URL https//github.com/idekerlab/pyNBS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Mutación
/
Neoplasias
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos