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Giant solitary primary intracranial lymphoma masquerading as meningioma: a case and review of literature.
Li, Junhong; Lei, Chuanfen; Richard, Seidu A; Liu, Yanhui.
Afiliación
  • Li J; Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guo Xue Xiang Road, Chengdu, 610041, PR, China.
  • Lei C; Department of Pathology, West China Hospital, Sichuan University, 37 Guo Xue Xiang Road, Chengdu, 610041, PR, China.
  • Richard SA; Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guo Xue Xiang Road, Chengdu, 610041, PR, China.
  • Liu Y; Department of Immunology, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu, 212013 PR, China.
Pan Afr Med J ; 28: 196, 2017.
Article en En | MEDLINE | ID: mdl-29610634
ABSTRACT
Non-Hodgkin's lymphomas (NHL) with intracranial origin are very rare and constitutes about 1-2% of primary central nervous system lymphomas (PCNSL). Diffuse large B cell lymphoma (DLBCL) is the most common subtype of NHL and mostly seen in immunocompromised patients. Therefore, the occurrence of giant solitary DLBCL in an immunocompetent patient is puzzling. We present a case of 68-year-old man who was admitted at our facility with a history of "hypomnesia of two (2) months" duration. Magnetic resonance imaging (MRI) revealed a space occupying lesion in the bilateral frontal lobe and corpus callosum measuring about 5.4cm * 4.6cm * 3.8cm with mixed signal intensities and vasogenic edema around the mass. Radiological, this mass was mistaken for meningioma until histopathological studies revealed DLBCL. Giant solitary primary intracranial lymphomas are very rare and can be mistake for meningioma even with very experience radiologist or neurosurgeon since the radiological features of PCNSL can be very unspecific. We achieved to total resection because of the giant and solitary nature of our case. The prognosis of PCNSL is general very poor when the patient is immunocompromised. In immunocompetent patients, who are well managed with surgery and chemotherapy, the overall survival and quality of life can very encouraging.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Linfoma de Células B Grandes Difuso / Neoplasias del Sistema Nervioso Central / Meningioma Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Humans / Male Idioma: En Revista: Pan Afr Med J Año: 2017 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Linfoma de Células B Grandes Difuso / Neoplasias del Sistema Nervioso Central / Meningioma Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Humans / Male Idioma: En Revista: Pan Afr Med J Año: 2017 Tipo del documento: Article País de afiliación: China