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Pharmacological validation of individual animal locomotion, temperature and behavioural analysis in group-housed rats using a novel automated home cage analysis system: A comparison with the modified Irwin test.
Tse, Karen; Sillito, Rowland; Keerie, Amy; Collier, Rachel; Grant, Claire; Karp, Natasha A; Vickers, Cathy; Chapman, Kathryn; Armstrong, J Douglas; Redfern, William S.
Afiliación
  • Tse K; Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Babraham Research Campus, Cambridge CB22 3AT, UK. Electronic address: karen.tse@astrazeneca.com.
  • Sillito R; Actual Analytics Ltd, Appleton Tower, 10 Crichton Street, Edinburgh EH8 9LE, UK.
  • Keerie A; Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Babraham Research Campus, Cambridge CB22 3AT, UK.
  • Collier R; Laboratory Animal Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Babraham Research Campus, Cambridge CB22 3AT, UK.
  • Grant C; Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Alderley Park, Cheshire SK10 4TG, UK.
  • Karp NA; Quantitative Biology, Discovery Science, IMED Biotech Unit, AstraZeneca, Cambridge Science Park, Cambridge CB4 0WG, UK.
  • Vickers C; NC3Rs, Gibbs Building, 215 Euston Road, London NW1 2BE, UK.
  • Chapman K; NC3Rs, Gibbs Building, 215 Euston Road, London NW1 2BE, UK.
  • Armstrong JD; Actual Analytics Ltd, Appleton Tower, 10 Crichton Street, Edinburgh EH8 9LE, UK; School of Informatics, University of Edinburgh, Appleton Tower, 11 Crichton Street, Edinburgh EH8 9LE, UK.
  • Redfern WS; Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Babraham Research Campus, Cambridge CB22 3AT, UK.
J Pharmacol Toxicol Methods ; 94(Pt 1): 1-13, 2018.
Article en En | MEDLINE | ID: mdl-29614333
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conducta Animal / Temperatura Corporal / Locomoción Límite: Animals Idioma: En Revista: J Pharmacol Toxicol Methods Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conducta Animal / Temperatura Corporal / Locomoción Límite: Animals Idioma: En Revista: J Pharmacol Toxicol Methods Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos