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Detection of calcium pyrophosphate dihydrate crystals in knee meniscus by dual-energy computed tomography.
Tanikawa, Hidenori; Ogawa, Ryo; Okuma, Kazunari; Harato, Kengo; Niki, Yasuo; Kobayashi, Shu; Nagura, Takeo.
Afiliación
  • Tanikawa H; Department of Orthopaedic Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi, Yokohama, Kanagawa, Japan. adriatic123sea@gmail.com.
  • Ogawa R; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.
  • Okuma K; Department of Orthopaedic Surgery, Saitama City Hospital, 2460 Minuma, Midoriku, Saitamashi, Saitama, Japan.
  • Harato K; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.
  • Niki Y; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.
  • Kobayashi S; Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.
  • Nagura T; Department of Clinical Biomechanics, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.
J Orthop Surg Res ; 13(1): 73, 2018 Apr 05.
Article en En | MEDLINE | ID: mdl-29622016
BACKGROUND: Calcium pyrophosphate dihydrate (CPPD) crystals are commonly observed in osteoarthritic joints. The aim of our study was to investigate the efficacy of a dual-energy computed tomography (DECT) for detecting CPPD crystals in knee meniscus. METHODS: Twenty-six patients undergoing primary total knee arthroplasty were included in the study. Radiographs of knee joint and synovial fluid specimens were analyzed for the presence of CPPD crystals. Meniscus extracted during surgery was scanned using DECT. Sensitivity and specificity of DECT and radiograph for detecting CPPD crystals were calculated against a reference standard (polarizing light microscopy of synovial fluid aspirate). Meniscus in which CPPD crystals were suspected with DECT was further examined to confirm the crystals using a polarized microscopy. RESULTS: CPPD crystals in synovial fluid were observed in 9 (36%) patients. The sensitivity and specificity of DECT in the detection of CPPD crystals, against microscopic identification, were 77.8 and 93.8%, respectively. The sensitivity and specificity of conventional radiography in the detection of CPPD crystals were 44.4 and 100%, respectively. DECT was able to detect the area where CPPD crystals were deposited in the meniscus. CONCLUSION: DECT provides good diagnostic sensitivity and specificity for detection of CPPD crystals in knee meniscus as well as spatial information about CPPD crystals. DECT is currently a research tool, but we believe that DECT can be a useful instrument to diagnose CPPD deposition disease, especially for the regions where aspiration is difficult to be performed such as pubic symphysis, atlantoaxial joint, interphalangeal joint.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirofosfato de Calcio / Condrocalcinosis / Menisco / Articulación de la Rodilla Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Orthop Surg Res Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirofosfato de Calcio / Condrocalcinosis / Menisco / Articulación de la Rodilla Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Orthop Surg Res Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido