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Can we incorporate geriatric assessment in the management of acute lymphoblastic leukemia in older adults?
Loh, Kah Poh; Liesveld, Jane L; O'Dwyer, Kristen M.
Afiliación
  • Loh KP; James P. Wilmot Cancer Institute, University of Rochester Medical Center, 601 Elmwood Avenue, Box 704, Rochester, NY 14620, United States. Electronic address: kahpoh_loh@urmc.rochester.edu.
  • Liesveld JL; James P. Wilmot Cancer Institute, University of Rochester Medical Center, 601 Elmwood Avenue, Box 704, Rochester, NY 14620, United States.
  • O'Dwyer KM; James P. Wilmot Cancer Institute, University of Rochester Medical Center, 601 Elmwood Avenue, Box 704, Rochester, NY 14620, United States.
J Geriatr Oncol ; 9(4): 296-301, 2018 07.
Article en En | MEDLINE | ID: mdl-29628416
Acute lymphoblastic leukemia (ALL) is an uncommon disease. Approximately 14% of new ALL cases occur in adults aged 60 and over, and the three-year overall survival in this population is poor at 12.8%. Older adults with ALL are heterogeneous in terms of their underlying health status, which can make treatment selection challenging given the disease rarity and limited inclusion of older patients in clinical trials. A comprehensive geriatric assessment (CGA) is a compilation of tools to assess multiple domains such as physical function and cognition, and may assist in guiding treatment selection and supportive care interventions. However, studies on the use of CGA are limited in older adults with ALL. In this review, we discuss the utility of CGA in patients with various hematologic malignancies. Using two patient cases of ALL, we also describe how CGA may be use to guide treatment and supportive care interventions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evaluación Geriátrica / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male Idioma: En Revista: J Geriatr Oncol Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evaluación Geriátrica / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male Idioma: En Revista: J Geriatr Oncol Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos