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An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
Garrison, Aaron T; Abouelhassan, Yasmeen; Kallifidas, Dimitris; Tan, Hao; Kim, Young S; Jin, Shouguang; Luesch, Hendrik; Huigens, Robert W.
Afiliación
  • Garrison AT; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), College of Pharmacy , University of Florida , Gainesville , Florida 32610 , United States.
  • Abouelhassan Y; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), College of Pharmacy , University of Florida , Gainesville , Florida 32610 , United States.
  • Kallifidas D; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), College of Pharmacy , University of Florida , Gainesville , Florida 32610 , United States.
  • Tan H; Department of Molecular Genetics & Microbiology, College of Medicine , University of Florida , Gainesville , Florida 32610 , United States.
  • Kim YS; Department of Molecular Genetics & Microbiology, College of Medicine , University of Florida , Gainesville , Florida 32610 , United States.
  • Jin S; Department of Molecular Genetics & Microbiology, College of Medicine , University of Florida , Gainesville , Florida 32610 , United States.
  • Luesch H; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), College of Pharmacy , University of Florida , Gainesville , Florida 32610 , United States.
  • Huigens RW; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), College of Pharmacy , University of Florida , Gainesville , Florida 32610 , United States.
J Med Chem ; 61(9): 3962-3983, 2018 05 10.
Article en En | MEDLINE | ID: mdl-29638121
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenazinas / Biopelículas / Halogenación / Antibacterianos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenazinas / Biopelículas / Halogenación / Antibacterianos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos