Rheumatic heart disease in Timor-Leste school students: an echocardiography-based prevalence study.
Med J Aust
; 208(7): 303-307, 2018 04 16.
Article
en En
| MEDLINE
| ID: mdl-29642817
ABSTRACT
OBJECTIVES:
To determine the prevalence of rheumatic heart disease (RHD) in school-aged children and young people in Timor-Leste.DESIGN:
Prospective cross-sectional survey. Echocardiography was performed by Australian cardiologists to determine the presence of RHD. Demographic data were also collected. Patients in whom RHD was detected were entered into a register to allow monitoring of adherence to secondary prophylaxis; the first dose of benzathine penicillin G (BPG) was administered on the day of screening.SETTING:
Schools in urban (Dili) and rural (Ermera) Timor-Leste.PARTICIPANTS:
School students aged 5-20 years. OUTCOMEMEASURES:
Definite and borderline RHD, as defined by World Heart Federation echocardiographic criteria.RESULTS:
1365 participants were screened; their median age was 11 years (IQR, 9-14 years), and 53% were girls. The estimated prevalence of definite RHD was 18.3 cases per 1000 population (95% CI, 12.3-27.0 per 1000), and of definite or borderline RHD 35.2 per 1000 (95% CI, 26.5-46.4 per 1000). Definite (adjusted odds ratio [aOR], 3.5; 95% CI, 1.3-9.4) and definite or borderline RHD (aOR, 2.7; 95% CI, 1.4-5.2) were more prevalent among girls than boys. Eleven children (0.8%) had congenital heart disease. Of the 25 children in whom definite RHD was identified, 21 (84%) received education and a first dose of BPG on the day of screening; all 25 have since received education about primary care for RHD and have commenced penicillin prophylaxis.CONCLUSIONS:
The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys. Community engagement is essential for ensuring follow-up and the effective delivery of secondary prophylaxis.Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cardiopatía Reumática
/
Ecocardiografía
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Med J Aust
Año:
2018
Tipo del documento:
Article