Hair disorders in patients with cancer.
J Am Acad Dermatol
; 80(5): 1179-1196, 2019 May.
Article
en En
| MEDLINE
| ID: mdl-29660422
ABSTRACT
Cytotoxic chemotherapies, molecularly targeted therapies, immunotherapies, radiotherapy, stem cell transplants, and endocrine therapies may lead to hair disorders, including alopecia, hirsutism, hypertrichosis, and pigmentary and textural hair changes. The mechanisms underlying these changes are varied and remain incompletely understood, hampering the development of preventive or therapeutic guidelines. The psychosocial impact of chemotherapy-induced alopecia has been well documented primarily in the oncology literature; however, the effect of other alterations, such as radiation-induced alopecia, hirsutism, and changes in hair color or texture on quality of life have not been described. This article reviews clinically significant therapy-related hair disorders in oncology patients, including the underlying pathophysiological mechanisms, severity grading scales, patient-reported quality of life questionnaires, management strategies, and future translational research opportunities.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Radioterapia
/
Crioterapia
/
Enfermedades del Cabello
/
Neoplasias
/
Antineoplásicos
Tipo de estudio:
Etiology_studies
/
Guideline
/
Qualitative_research
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2019
Tipo del documento:
Article