Enzyme-Treated Asparagus Extract (ETAS) Facilitates the Turnover of UV-B-Irradiated Keratinocytes.
J Nutr Sci Vitaminol (Tokyo)
; 64(2): 138-142, 2018.
Article
en En
| MEDLINE
| ID: mdl-29710031
ABSTRACT
Enzyme-treated asparagus extract (ETAS) is prepared from the lower, residual parts of asparagus, and some functionalities, such as anti-oxidative and neuroprotective activities, have been suggested. The purpose of the present study was to investigate the effects of ETAS on photoaging in the epidermal layer of the skin using cultured keratinocytes. Normal human epidermal keratinocytes were irradiated or left unirradiated with UV-B (10 mJ/cm2) and incubated with ETAS (0.5 or 2 mg/mL) or vehicle. After 3 or 13 h, molecular examinations were performed, and after 24 or 48 h, cell viabilities were determined by a CCK-8 assay. ETAS addition may induce keratinocyte migration and proliferation as well as apoptosis under molecular examination. These results suggest that ETAS might accelerate turnover of keratinocytes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Rayos Ultravioleta
/
Extractos Vegetales
/
Queratinocitos
/
Envejecimiento de la Piel
/
Asparagus
/
Epidermis
Límite:
Humans
Idioma:
En
Revista:
J Nutr Sci Vitaminol (Tokyo)
Año:
2018
Tipo del documento:
Article