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Expression on hypoxia-inducible factor-1α in human tegumentary leishmaniosis caused by Leishmania braziliensis
Rocha, Francisca Janaina Soares; Pereira, Caroline Louise Diniz; de Melo, Fabio Lopes; Soares, Cynthia Regina Pedrosa; Paz, Silvania Tavares; Giorgio, Selma.
Afiliación
  • Rocha FJS; Department of Tropical Medicine, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670-901, Recife, Pernambuco, Brazil
  • Pereira CLD; Department of Tropical Medicine, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670-901, Recife, Pernambuco, Brazil
  • de Melo FL; Department of Parasitology, Aggeu Magalhães Research Center, Prof. Moraes Rego Av., 50670-420, Recife, Pernambuco, Brazil
  • Soares CRP; Department of Parasitology, Aggeu Magalhães Research Center, Prof. Moraes Rego Av., 50670-420, Recife, Pernambuco, Brazil
  • Paz ST; Department of Pathology, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670- 901, Recife, Pernambuco, Brazil
  • Giorgio S; Department of Animal Biology, State University of Campinas, Monteiro Lobato St. 255, 13083-862, Campinas, São Paulo, Brazil
Ann Parasitol ; 64(1): 73­76, 2018.
Article en En | MEDLINE | ID: mdl-29717578
ABSTRACT
Several immune markers have been studied in controlling American tegumentary leishmaniosis based on mouse models. However, there is a lack of studies regarding human tegumentary leishmaniosis caused by Leishmania braziliensis. In this study, hypoxia-inducible factor-1α was found to be an important effector element in the localized control of human cutaneous and mucocutaneous lesions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leishmania braziliensis / Regulación de la Expresión Génica / Leishmaniasis Cutánea / Subunidad alfa del Factor 1 Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Adult / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Ann Parasitol Año: 2018 Tipo del documento: Article País de afiliación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leishmania braziliensis / Regulación de la Expresión Génica / Leishmaniasis Cutánea / Subunidad alfa del Factor 1 Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Adult / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Ann Parasitol Año: 2018 Tipo del documento: Article País de afiliación: Brasil