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LC-MS/MS assay for N1-methylnicotinamide in humans, an endogenous probe for renal transporters.
Luo, Lina; Kay, Jared; Zhang, Jenny; Holliman, Christopher L; Rodrigues, A David; Dowty, Martin; Banfield, Christopher; Ramanathan, Ragu.
Afiliación
  • Luo L; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
  • Kay J; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
  • Zhang J; Clinical Assay Group, Global Product Development, Pfizer, Inc., 445 Eastern Pint Road, Groton, CT 06340, USA.
  • Holliman CL; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
  • Rodrigues AD; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
  • Dowty M; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
  • Banfield C; Department of Clinical Pharmacology, Research & Development, Pfizer, Inc., 1 Portland Street, Cambridge, MA 02139, USA.
  • Ramanathan R; Department of Pharmacokinetics, Dynamics & Metabolism, Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT 06340, USA.
Bioanalysis ; 10(9): 673-689, 2018 May 01.
Article en En | MEDLINE | ID: mdl-29749253
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Niacinamida / Biomarcadores Farmacológicos / Transportador 2 de Cátion Orgánico / Riñón Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Bioanalysis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Niacinamida / Biomarcadores Farmacológicos / Transportador 2 de Cátion Orgánico / Riñón Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Bioanalysis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido