Quantitative multispectral ex vivo optical evaluation of human ovarian tissue using spatial frequency domain imaging.
Biomed Opt Express
; 9(5): 2451-2456, 2018 May 01.
Article
en En
| MEDLINE
| ID: mdl-29761000
ABSTRACT
About 85-90% of all ovarian cancers are carcinomas; these manifest clinically as mass-forming epithelial proliferations involving the ovary. In this study, a visible light spatial frequency domain imaging (SFDI) system was used for multispectral ex vivo imaging and quantitative evaluation of freshly excised benign and malignant human ovarian tissues. A total of 14 ovaries from 11 patients undergoing oophorectomy were investigated. Using a logistic regression model with seven significant spectral and spatial features extracted from SFDI images, a sensitivity of 94.06% and specificity of 93.53% were achieved for prediction of histologically confirmed invasive carcinoma.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Biomed Opt Express
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos