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The BET bromodomain inhibitor apabetalone induces apoptosis of latent HIV-1 reservoir cells following viral reactivation.
Zhang, Xuan-Xuan; Lin, Jian; Liang, Tai-Zhen; Duan, Heng; Tan, Xing-Hua; Xi, Bao-Min; Li, Lin; Liu, Shu-Wen.
Afiliación
  • Zhang XX; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lin J; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Liang TZ; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Duan H; Department of Pharmacy, Stomatological Hospital of Southern Medical University and Guangdong Provincial Stomatological Hospital, Guangzhou, 510280, China.
  • Tan XH; Department of Infectious Disease, Guangzhou No 8 People's Hospital, Guangzhou, 510060, China.
  • Xi BM; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Li L; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. li75lin@126.com.
  • Liu SW; Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, State Key Laboratory of Organ Failure Research, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. liusw@smu.edu.cn
Acta Pharmacol Sin ; 40(1): 98-110, 2019 Jan.
Article en En | MEDLINE | ID: mdl-29789664
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: VIH-1 / Apoptosis / Latencia del Virus / Fármacos Anti-VIH / Quinazolinonas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: VIH-1 / Apoptosis / Latencia del Virus / Fármacos Anti-VIH / Quinazolinonas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos