Renoprotective effect of the isoflavonoid biochanin A against cisplatin induced acute kidney injury in mice: Effect on inflammatory burden and p53 apoptosis.

Suliman, Faiha A; Khodeer, Dina M; Ibrahiem, Afaf; Mehanna, Eman T; El-Kherbetawy, Mohamed K; Mohammad, Hala M F; Zaitone, Sawsan A; Moustafa, Yasser M

Suliman, Faiha A; Khodeer, Dina M; Ibrahiem, Afaf; Mehanna, Eman T; El-Kherbetawy, Mohamed K; Mohammad, Hala M F; Zaitone, Sawsan A; Moustafa, Yasser M.

Afiliación

Suliman FA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. Electronic address: faihaabobaker@yahoo.com.
Khodeer DM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. Electronic address: dina_khoudaer@pharm.suez.edu.eg.
Ibrahiem A; Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Mehanna ET; Biochemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. Electronic address: eman.taha@pharm.suez.edu.eg.
El-Kherbetawy MK; Pathology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Mohammad HMF; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt. Electronic address: hala_mohamed@med.suez.edu.eg.
Zaitone SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia. Electronic address: sawsan_zaytoon@pharm.suez.edu.eg.
Moustafa YM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. Electronic address: yasser_mostafa@pharm.suez.edu.eg.

Int Immunopharmacol ; 61: 8-19, 2018 Aug.

Article en En | MEDLINE | ID: mdl-29793166

Asunto(s)

Lesión Renal Aguda/tratamiento farmacológico; Antiinflamatorios/uso terapéutico; Genisteína/uso terapéutico; Riñón/efectos de los fármacos; Proteína p53 Supresora de Tumor/metabolismo; Lesión Renal Aguda/inducido químicamente; Animales; Apoptosis/efectos de los fármacos; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; Caspasa 3/metabolismo; Cisplatino; Creatinina/sangre; Citocinas/metabolismo; Regulación de la Expresión Génica; Genisteína/química; Mediadores de Inflamación/metabolismo; Isoflavonas/química; Riñón/patología; Ratones; Necrosis; Proteína p53 Supresora de Tumor/genética; Proteínas Supresoras de Tumor/genética; Proteínas Supresoras de Tumor/metabolismo; Urea/metabolismo

Palabras clave

Acute kidney injury; Biochanin A; Cisplatin; Inflammation; PUMA; p53 apoptosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Genisteína / Lesión Renal Aguda / Riñón / Antiinflamatorios Límite: Animals Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Países Bajos

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