Plasmodium falciparum Plasmepsin 2 Duplications, West Africa.
Emerg Infect Dis
; 24(8)2018 08.
Article
en En
| MEDLINE
| ID: mdl-29798744
ABSTRACT
Dihydroartemisinin/piperaquine (DHA/PPQ) is increasingly deployed as antimalaria drug in Africa. We report the detection in Mali of Plasmodium falciparum infections carrying plasmepsin 2 duplications (associated with piperaquine resistance) in 7/65 recurrent infections within 2 months after DHA/PPQ treatment. These findings raise concerns about the long-term efficacy of DHA/PPQ treatment in Africa.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmodium falciparum
/
Quinolinas
/
Ácido Aspártico Endopeptidasas
/
Malaria Falciparum
/
Artemisininas
/
Antimaláricos
Límite:
Humans
País/Región como asunto:
Africa
Idioma:
En
Revista:
Emerg Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2018
Tipo del documento:
Article