Single cell genomics to study DNA and chromosome changes in human gametes and embryos.

Blanshard, Robert C; Chen, Chongyi; Xie, Xiaoliang Sunney; Hoffmann, Eva R

Blanshard, Robert C; Chen, Chongyi; Xie, Xiaoliang Sunney; Hoffmann, Eva R.

Afiliación

Blanshard RC; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, United Kingdom; Clinical Genomics Group, Illumina Inc., Fulbourn, United Kingdom.
Chen C; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, United States.
Xie XS; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, United States; Beijing Advanced Innovation Center for Genomics, Beijing, China. Electronic address: xie@chemistry.harvard.edu.
Hoffmann ER; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, United Kingdom; Center for Chromosome Stability, University of Copenhagen, Copenhagen, Denmark. Electronic address: eva@sund.ku.dk.

Methods Cell Biol ; 144: 441-457, 2018.

Article en En | MEDLINE | ID: mdl-29804682

Asunto(s)

Cromosomas Humanos/metabolismo; ADN/metabolismo; Embrión de Mamíferos/metabolismo; Genoma Humano; Genómica/métodos; Células Germinativas/metabolismo; Análisis de la Célula Individual/métodos; Humanos; Oocitos/metabolismo; Polimorfismo de Nucleótido Simple/genética

Palabras clave

Embryos; Genome stability; Oocytes; Single cell DNA sequencing; Single cell genomics; Whole genome amplification

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Genoma Humano / Cromosomas Humanos / Genómica / Embrión de Mamíferos / Análisis de la Célula Individual / Células Germinativas Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Methods Cell Biol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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