Your browser doesn't support javascript.
loading
Heart Protective Effects of Electroacupuncture in an Animal Experimental Study with Delayed Fluid Resuscitation after Hemorrhagic Shock.
Wang, Huan; Liu, Zhen; Liu, Yuanshi; Tong, Zhanqi; Qian, Yan; Chen, Liping; Jiang, Bin; Lin, Mingxiong; Yang, Tao; Gao, Lu; Chen, Mingjun; Litscher, Daniela; Wang, Lu; Litscher, Gerhard.
Afiliación
  • Wang H; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Liu Z; TCM Research Center Graz, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and Research Unit for Complementary and Integrative Laser Medicine, Medical University of Graz, 8036 Graz, Austria.
  • Liu Y; Department of Gastroenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
  • Tong Z; Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
  • Qian Y; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Chen L; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Jiang B; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Lin M; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Yang T; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Gao L; Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
  • Chen M; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Litscher D; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Wang L; Department of TCM and Acupuncture, People's Liberation Army General Hospital, Beijing 100853, China.
  • Litscher G; TCM Research Center Graz, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and Research Unit for Complementary and Integrative Laser Medicine, Medical University of Graz, 8036 Graz, Austria.
Article en En | MEDLINE | ID: mdl-29805466
Fluid resuscitation could hardly be performed immediately after fatal hemorrhagic shock in outpatients. We investigated whether electroacupuncture (EA) at Zusanli (ST36) could prevent fatal hemorrhagic shock induced heart failure with delayed fluid resuscitation and whether the protective role of EA is related to the autonomic nervous system. Sixty Sprague Dawley rats were randomly divided into five groups (n = 12 each): group of sham hemorrhagic shock (SHAM), group of EA, group of sham EA (SEA), group of delayed fluid resuscitation with EA (EA + DR), and group of delayed fluid resuscitation with SEA (SEA + DR). After blood loss for 6 hours, caspase-3 activity and positive rate of TUNEL in EA + DR group were significantly lower than in other hemorrhagic shock groups (e.g., versus SEA + DR: 0.156 ± 0.039 versus 0.301 ± 0.042; P < 0.05). Immediately EA treatment after the blood loss enhanced the protective effect of delayed resuscitation on the cardiac tissue of hemorrhagic shock rats. Considering the significant changes of epinephrine (137.8 ± 6.9 ng/L versus 98.6 ± 7.4 ng/L; P < 0.05) and acetylcholine (405 ± 8.6 pmol/L versus 341 ± 10.1 pmol/L; P < 0.05) after EA treatment (SEA + DR versus EA + DR), this cardiac protective effect may be related to regulation of the autonomic nervous system.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Evid Based Complement Alternat Med Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Evid Based Complement Alternat Med Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos