Expression and significance of RRBP1 in esophageal carcinoma.
Cancer Manag Res
; 10: 1243-1249, 2018.
Article
en En
| MEDLINE
| ID: mdl-29844703
ABSTRACT
OBJECTIVE:
This study was to investigate the expression and clinical significance of RRBP1 in esophageal carcinoma. MATERIALS ANDMETHODS:
RRBP1 expression was detected in 120 esophageal carcinoma and matched adjacent normal tissues, and the relationship of RRBP1 with clinicopathological characteristics and prognosis was analyzed.RESULTS:
RRBP1 was highly expressed in esophageal carcinoma tissues compared with matched adjacent normal tissues (P<0.05). Moreover, RRBP1 expression was associated with T stage, lymph node metastasis, and TNM stage in esophageal carcinoma (P<0.05). Survival analysis revealed that RRBP1, T stage, lymph node metastasis, and TNM stage were significantly associated with patients' prognosis.CONCLUSION:
RRBP1 is highly expressed in esophageal carcinoma and can serve as a potential biomarker to predict patients' prognosis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Cancer Manag Res
Año:
2018
Tipo del documento:
Article
País de afiliación:
China