TORCH serologies and specific IgM antibody determination in acquired and congenital infections.
Ann Clin Lab Sci
; 15(3): 204-11, 1985.
Article
en En
| MEDLINE
| ID: mdl-2986514
ABSTRACT
Except for rubella testing, routine TORCH serology screens in prenatal care are of little use. Individual TORCH tests may, however, be useful based on the clinical presentation and history of the patient. The laboratory test of choice for diagnosing cytomegalovirus (CMV) and herpes simplex virus (HSV) infections is culture isolation for the virus. The presence for specific IgM antibodies in neonates is diagnostic of congenital infection. In adults, IgM antibody results should be interpreted along with the clinical findings and history of the patient. IgM antibodies may persist for months and even years and may be detected during reactivation of latent virus infections. Serum fractionation should always be performed in IgM antibody testing to avoid false positive results owing to rheumatoid factors and false negative results owing to competing levels of specific IgG antibodies. With a single serum specimen, specific IgM antibody detection may be helpful in differentiating between a recent versus past infection.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
/
Atención Prenatal
/
Rubéola (Sarampión Alemán)
/
Inmunoglobulina M
/
Toxoplasmosis
/
Infecciones por Citomegalovirus
/
Herpes Simple
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Ann Clin Lab Sci
Año:
1985
Tipo del documento:
Article