The role of the PLR-NLR combination in the prediction of the presence of Helicobacter pylori and its associated complications.
Saudi J Gastroenterol
; 24(5): 294-300, 2018.
Article
en En
| MEDLINE
| ID: mdl-29873316
ABSTRACT
BACKGROUND/AIM:
The aim of this study was to investigate the role of the platelet-to-lymphocyte ratio (PLR)-neutrophil-to-lymphocyte ratio (NLR) combination, in the prediction of the presence of Helicobacter pylori (HP) and its associated complications in the gastrointestinal system. PATIENTS ANDMETHODS:
In all, 1289 patients who underwent esophagogastroduodenoscopy and biopsy for HP were included in the study.RESULTS:
The ratio of patients with moderate and severe chronic gastritis was higher in HP (+) group than HP (-) group. The ratio of patients with levels 1-3 atrophy and intestinal metaplasia was higher in HP (+) group. Compared with HP (-) group, HP (+) had higher PLR and NLR levels. The ratio of HP (+) patients was higher in high-risk group compared with low- and medium-risk groups. HP invasion stage, the intestinal metaplasia level, and the ratio of patients with atrophy level "3" were higher in high-risk group compared with low- and medium-risk groups. Regression analysis showed that the PLR-NLR combination was an independent risk factor for both HP presence and moderate and severe chronic gastritis.CONCLUSION:
We found the PLR-NLR combination to be a good predictor of HP presence and gastrointestinal complications associated with HP.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plaquetas
/
Linfocitos
/
Helicobacter pylori
/
Infecciones por Helicobacter
/
Gastritis
/
Neutrófilos
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Saudi J Gastroenterol
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Turquía