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Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
Hirano, Tomoya; Fujiwara, Takashi; Niwa, Hideaki; Hirano, Michitake; Ohira, Kasumi; Okazaki, Yusuke; Sato, Shin; Umehara, Takashi; Maemoto, Yuki; Ito, Akihiro; Yoshida, Minoru; Kagechika, Hiroyuki.
Afiliación
  • Hirano T; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Fujiwara T; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Niwa H; Epigenetics Drug Discovery Unit, RIKEN Center for Life Science Technologies (CLST), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.
  • Hirano M; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Ohira K; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Okazaki Y; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Sato S; Epigenetics Drug Discovery Unit, RIKEN Center for Life Science Technologies (CLST), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.
  • Umehara T; Epigenetics Drug Discovery Unit, RIKEN Center for Life Science Technologies (CLST), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.
  • Maemoto Y; School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Ito A; School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Yoshida M; Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science (CSRS), 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Kagechika H; Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science (CSRS), 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
ChemMedChem ; 13(15): 1530-1540, 2018 08 10.
Article en En | MEDLINE | ID: mdl-29882380
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: N-Metiltransferasa de Histona-Lisina / Ciproheptadina / Inhibidores Enzimáticos Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: N-Metiltransferasa de Histona-Lisina / Ciproheptadina / Inhibidores Enzimáticos Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania