Importance of target-mediated drug disposition for small molecules.

Smith, Dennis A; van Waterschoot, Robert A B; Parrott, Neil J; Olivares-Morales, Andrés; Lavé, Thierry; Rowland, Malcolm

Smith, Dennis A; van Waterschoot, Robert A B; Parrott, Neil J; Olivares-Morales, Andrés; Lavé, Thierry; Rowland, Malcolm.

Afiliación

Smith DA; Department of Chemistry, University of Cape Town, Cape Town, South Africa.
van Waterschoot RAB; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland. Electronic address: robert.van_waterschoot@roche.com.
Parrott NJ; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Olivares-Morales A; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Lavé T; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Rowland M; Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester, Manchester, UK.

Drug Discov Today ; 23(12): 2023-2030, 2018 12.

Article en En | MEDLINE | ID: mdl-29928850

Asunto(s)

Bibliotecas de Moléculas Pequeñas/farmacocinética; Animales; Ensayos Clínicos como Asunto; Sistemas de Liberación de Medicamentos/métodos; Humanos; Distribución Tisular/fisiología

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bibliotecas de Moléculas Pequeñas Límite: Animals / Humans Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2018 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido

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