The effect of mirabegron, used for overactive bladder treatment, on female sexual function: a prospective controlled study.
BMC Urol
; 18(1): 61, 2018 Jun 25.
Article
en En
| MEDLINE
| ID: mdl-29940933
ABSTRACT
BACKGROUND:
Αim of the study was to determine the effect of mirabegron, used for overactive bladder (OAB) treatment, on female sexual function.METHODS:
Eighty five sexually active women suffering from overactive bladder were prospectively enrolled in this study. Females were divided into two groups. In Group A (control), 48 patients received no treatment and in Group B, 37 patients received mirabegron 50 mg/daily for 3 months. Patients were evaluated with FSFI-Gr at the beginning of the study and again after a period of 3 months.RESULTS:
In Group B, there was a significant increase post-treatment compared to baseline (p < 0.001) in total FSFI (20.3 (3.8) to 26.6 (4.2)) and all domains (desire 3.0 (1.2) to 4.8 (1.2)), arousal 3.0 (0.8) to 4.8 (0.9), lubrication 3.9 (1.1) to 4.8 (1.2), orgasm 3.6 (0.8) to 4.8 (1.0), satisfaction 3.2 (0.4) to 4.0 (0.8) and pain 3.2 (0.8) to 4.4 (1.2)). In Group A, there were no statistically significant changes in pre- and post-observation values.CONCLUSIONS:
This study is one of the few demonstrating that management of OAB with mirabegron improves female sexual function. TRIAL REGISTRATION TRN ISRCTN17199301 , 20/10/2017, retrospectively registered.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Orgasmo
/
Tiazoles
/
Vejiga Urinaria Hiperactiva
/
Agonistas de Receptores Adrenérgicos beta 3
/
Agentes Urológicos
/
Acetanilidas
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
BMC Urol
Asunto de la revista:
UROLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Grecia