NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo.

Jia, Gang; Han, Yong; An, Yanli; Ding, Yinan; He, Chen; Wang, Xihui; Tang, Qiusha

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo.

Jia, Gang; Han, Yong; An, Yanli; Ding, Yinan; He, Chen; Wang, Xihui; Tang, Qiusha.

Afiliación

Jia G; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
Han Y; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
An Y; Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
Ding Y; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
He C; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
Wang X; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China.
Tang Q; Medical School of Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, China. Electronic address: 101010487@seu.edu.cn.

Biomaterials ; 178: 302-316, 2018 09.

Article en En | MEDLINE | ID: mdl-29982104

Asunto(s)

Neoplasias Encefálicas/diagnóstico por imagen; Neoplasias Encefálicas/terapia; Exosomas/metabolismo; Glioma/diagnóstico por imagen; Glioma/terapia; Terapia Molecular Dirigida; Neuropilina-1/metabolismo; Animales; Neoplasias Encefálicas/patología; Línea Celular Tumoral; Curcumina/uso terapéutico; Exosomas/ultraestructura; Femenino; Glioma/patología; Humanos; Estimación de Kaplan-Meier; Nanopartículas de Magnetita/química; Nanopartículas de Magnetita/ultraestructura; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Péptidos/química; Células RAW 264.7; Reproducibilidad de los Resultados

Palabras clave

Bloodbrain barrier; Curcumin; Exosome; Glioma; Neuropilin-1; SPION

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Neuropilina-1 / Exosomas / Terapia Molecular Dirigida / Glioma Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Biomaterials Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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