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Design, synthesis and biological evaluation of 3-piperazinecarboxylate sarsasapogenin derivatives as potential multifunctional anti-Alzheimer agents.
Yang, Gui-Xiang; Ge, Song-Lan; Wu, Yan; Huang, Jin; Li, Shi-Liang; Wang, Rui; Ma, Lei.
Afiliación
  • Yang GX; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
  • Ge SL; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
  • Wu Y; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
  • Huang J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
  • Li SL; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China. Electronic address: slli403@163.com.
  • Wang R; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China. Electronic address: ruiwang@ecust.edu.cn.
  • Ma L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China. Electronic address: malei@ecust.edu.cn.
Eur J Med Chem ; 156: 206-215, 2018 Aug 05.
Article en En | MEDLINE | ID: mdl-30006165
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Espirostanos / Diseño de Fármacos / Péptidos beta-Amiloides / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article Pais de publicación: Francia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Espirostanos / Diseño de Fármacos / Péptidos beta-Amiloides / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article Pais de publicación: Francia