Iodine-Catalyzed Chemoselective C-N Bond-Forming Reactions Using Benzylic or Cinnamyl Alcohols with Heterocyclic Thiols and Thiones.
J Org Chem
; 83(18): 11145-11153, 2018 Sep 21.
Article
en En
| MEDLINE
| ID: mdl-30032620
ABSTRACT
A chemoselective formation of C-N bond catalyzed by iodine has been developed using heterocyclic thiols and thiones. The reaction occurs at the nitrogen center over the sulfur, leading to the amination against the traditional sulfenylation. A wide variety of allylic and benzylic alcohols serve as coupling partners. This method showed a good tolerance toward 1 H-tetrazole-5-thiol, 5-methyl-1,3,4-thiadiazole-2-thiol, benzo[ d]thiazole-2(3 H)-thione, and benzo[ d]oxazole-2(3 H)-thione derivatives.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Año:
2018
Tipo del documento:
Article
País de afiliación:
India