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Increased Synthesis of MCL-1 Protein Underlies Initial Survival of EGFR-Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target.
Song, Kyung-A; Hosono, Yasuyuki; Turner, Crystal; Jacob, Sheeba; Lochmann, Timothy L; Murakami, Yoshiko; Patel, Neha U; Ham, Jungoh; Hu, Bin; Powell, Krista M; Coon, Colin M; Windle, Brad E; Oya, Yuko; Koblinski, Jennifer E; Harada, Hisashi; Leverson, Joel D; Souers, Andrew J; Hata, Aaron N; Boikos, Sosipatros; Yatabe, Yasushi; Ebi, Hiromichi; Faber, Anthony C.
Afiliación
  • Song KA; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Hosono Y; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, Japan.
  • Turner C; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Jacob S; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Lochmann TL; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Murakami Y; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan.
  • Patel NU; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Ham J; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Hu B; Department of Pathology, VCU School of Medicine, Richmond, Virginia.
  • Powell KM; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Coon CM; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Windle BE; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Oya Y; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, Japan.
  • Koblinski JE; Department of Pathology, VCU School of Medicine, Richmond, Virginia.
  • Harada H; Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Richmond, Virginia.
  • Leverson JD; AbbVie, North Chicago, Illinois.
  • Souers AJ; AbbVie, North Chicago, Illinois.
  • Hata AN; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Boikos S; Division of Hematology, Oncology and Palliative Care, Virginia Commonwealth University, Massey Cancer Center, Richmond, Virginia.
  • Yatabe Y; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan.
  • Ebi H; Precision Medicine Center, Aichi Cancer Center, Nagoya, Japan.
  • Faber AC; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, Japan. acfaber@vcu.edu hebi@aichi-cc.jp.
Clin Cancer Res ; 24(22): 5658-5672, 2018 11 15.
Article en En | MEDLINE | ID: mdl-30087143

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Neoplasias Pulmonares / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Neoplasias Pulmonares / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article