Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure.

Pepin, Mark E; Ha, Chae-Myeong; Crossman, David K; Litovsky, Silvio H; Varambally, Sooryanarayana; Barchue, Joseph P; Pamboukian, Salpy V; Diakos, Nikolaos A; Drakos, Stavros G; Pogwizd, Steven M; Wende, Adam R

Pepin, Mark E; Ha, Chae-Myeong; Crossman, David K; Litovsky, Silvio H; Varambally, Sooryanarayana; Barchue, Joseph P; Pamboukian, Salpy V; Diakos, Nikolaos A; Drakos, Stavros G; Pogwizd, Steven M; Wende, Adam R.

Afiliación

Pepin ME; Dept of Pathology, Div of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Ha CM; Dept of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Crossman DK; Dept of Pathology, Div of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Litovsky SH; Dept of Genetics, Heflin Center for Genomic Science, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Varambally S; Dept of Pathology, Div of Anatomic Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Barchue JP; Dept of Pathology, Div of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Pamboukian SV; Dept of Medicine, Div of Cardiovascular Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Diakos NA; Dept of Medicine, Div of Cardiovascular Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Drakos SG; Dept of Internal Medicine, Div of Cardiovascular Medicine & Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT, 84108, USA.
Pogwizd SM; Dept of Internal Medicine, Div of Cardiovascular Medicine & Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT, 84108, USA.
Wende AR; Dept of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.

Lab Invest ; 99(3): 371-386, 2019 03.

Article en En | MEDLINE | ID: mdl-30089854

Asunto(s)

Metilación de ADN; Insuficiencia Cardíaca/genética; Isquemia Miocárdica/genética; Anciano; Animales; Línea Celular; Islas de CpG; Proteína Potenciadora del Homólogo Zeste 2/genética; Proteína Potenciadora del Homólogo Zeste 2/metabolismo; Epigénesis Genética; Perfilación de la Expresión Génica; Genoma Humano; Insuficiencia Cardíaca/metabolismo; Ventrículos Cardíacos/metabolismo; Humanos; Factores de Transcripción de Tipo Kruppel/genética; Factores de Transcripción de Tipo Kruppel/metabolismo; Masculino; Persona de Mediana Edad; Modelos Cardiovasculares; Isquemia Miocárdica/metabolismo; Miocardio/metabolismo; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Ratas; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Análisis de Secuencia de ARN

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isquemia Miocárdica / Metilación de ADN / Insuficiencia Cardíaca Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Humans / Male / Middle aged Idioma: En Revista: Lab Invest Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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