Anti-inflammatory Action of Metformin with Respect to CX3CL1/CX3CR1 Signaling in Human Placental Circulation in Normal-Glucose Versus High-Glucose Environments.

Szukiewicz, D; Szewczyk, Grzegorz; Pyzlak, Michal; Stangret, Aleksandra; Bachanek, Michal; Trojanowski, Seweryn; Alkhalayla, Habib; Wejman, Jaroslaw

Szukiewicz, D; Szewczyk, Grzegorz; Pyzlak, Michal; Stangret, Aleksandra; Bachanek, Michal; Trojanowski, Seweryn; Alkhalayla, Habib; Wejman, Jaroslaw.

Afiliación

Szukiewicz D; Department of General & Experimental Pathology with Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Pawinskiego 3C, 02-106, Warsaw, Poland. Dszukiewicz@hotmail.com.
Szewczyk G; Department of General & Experimental Pathology with Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Pawinskiego 3C, 02-106, Warsaw, Poland.
Pyzlak M; Department of General & Experimental Pathology with Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Pawinskiego 3C, 02-106, Warsaw, Poland.
Stangret A; Department of General & Experimental Pathology with Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Pawinskiego 3C, 02-106, Warsaw, Poland.
Bachanek M; Department of Obstetrics & Gynecology, Second Faculty of Medicine, Medical University of Warsaw, Kondratowicza 8, 03-242, Warsaw, Poland.
Trojanowski S; Department of Obstetrics & Gynecology, Second Faculty of Medicine, Medical University of Warsaw, Kondratowicza 8, 03-242, Warsaw, Poland.
Alkhalayla H; Department of Obstetrics & Gynecology, Second Faculty of Medicine, Medical University of Warsaw, Kondratowicza 8, 03-242, Warsaw, Poland.
Wejman J; Department of Pathology, Professor Witold Orlowski Public Clinical Hospital, Medical Center for Postgraduate Education, Czerniakowska 231, 00-416, Warsaw, Poland.

Inflammation ; 41(6): 2246-2264, 2018 Dec.

Article en En | MEDLINE | ID: mdl-30097812

Asunto(s)

Glucemia; Receptor 1 de Quimiocinas CX3C/metabolismo; Quimiocina CX3CL1/metabolismo; Metformina/farmacocinética; Circulación Placentaria/efectos de los fármacos; Adulto; Animales; Antiinflamatorios/farmacología; Femenino; Humanos; Hiperglucemia; Hipoglucemiantes/farmacología; FN-kappa B/efectos de los fármacos; FN-kappa B/metabolismo; Embarazo; Receptores Tipo I de Factores de Necrosis Tumoral/efectos de los fármacos; Receptores Tipo I de Factores de Necrosis Tumoral/metabolismo; Transducción de Señal/efectos de los fármacos; Factor de Necrosis Tumoral alfa/metabolismo; Adulto Joven

Palabras clave

chemokine CX3CL1; fractalkine; fractalkine receptor; high-glucose environment; human placenta; metformin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Circulación Placentaria / Quimiocina CX3CL1 / Receptor 1 de Quimiocinas CX3C / Metformina Límite: Adult / Animals / Female / Humans / Pregnancy Idioma: En Revista: Inflammation Año: 2018 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos

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