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Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108.
Pallach, Mateusz; Di Lorenzo, Flaviana; Facchini, Fabio Alessandro; Gully, Djamel; Giraud, Eric; Peri, Francesco; Duda, Katarzyna A; Molinaro, Antonio; Silipo, Alba.
Afiliación
  • Pallach M; Department of Chemical Sciences, University of Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, I-80126 Napoli, Italy. Electronic address: mateusz.pallach@unina.it.
  • Di Lorenzo F; Department of Chemical Sciences, University of Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, I-80126 Napoli, Italy. Electronic address: flaviana.dilorenzo@unina.it.
  • Facchini FA; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy. Electronic address: f.facchini@campus.unimib.it.
  • Gully D; IRD, Laboratoire des Symbioses Tropicales et Méditerranéennes (LSTM), UMR IRD/SupAgro/INRA/UM2/CIRAD, TA-A82/J - Campus de Baillarguet, 34398 Montpellier Cedex 5, France. Electronic address: djamel.gully@ird.fr.
  • Giraud E; IRD, Laboratoire des Symbioses Tropicales et Méditerranéennes (LSTM), UMR IRD/SupAgro/INRA/UM2/CIRAD, TA-A82/J - Campus de Baillarguet, 34398 Montpellier Cedex 5, France. Electronic address: eric.giraud@ird.fr.
  • Peri F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy. Electronic address: francesco.peri@unimib.it.
  • Duda KA; Junior Group of Allergobiochemistry, Research Center Borstel, Leibniz Lung Center, 23845 Borstel, Germany; Airway Research Center North (ARCN), German Center for Lung Research, Germany. Electronic address: kduda@fz-borstel.de.
  • Molinaro A; Department of Chemical Sciences, University of Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, I-80126 Napoli, Italy. Electronic address: molinaro@unina.it.
  • Silipo A; Department of Chemical Sciences, University of Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, I-80126 Napoli, Italy. Electronic address: silipo@unina.it.
Int J Biol Macromol ; 119: 1027-1035, 2018 Nov.
Article en En | MEDLINE | ID: mdl-30098357
ABSTRACT
Acetobacter pasteurianus is an acetic acid-producing Gram-negative bacterium commonly found associated with plants and plant products and widely used in the production of fermented foods, such as kefir and vinegar. Due to the acid conditions of the bacterium living habitat, uncommon structural features composing its cell envelope are expected. In the present work we have investigated the A. pasteurianus CIP103108 lipopolysaccharide (LPS) structure and immunoactivity. The structure of the lipid A and of two different O-polysaccharides was assessed. Furthermore, immunological studies with human cells showed a low immunostimulant activity of the isolated LPS, in addition to a slight capability to lower the NF-kB activation upon stimulation by toxic LPS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetobacter / Lipopolisacáridos / Mediadores de Inflamación Límite: Humans Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetobacter / Lipopolisacáridos / Mediadores de Inflamación Límite: Humans Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article