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Biotransformation of [14C]-ixazomib in patients with advanced solid tumors: characterization of metabolite profiles in plasma, urine, and feces.
Pusalkar, Sandeepraj; Plesescu, Mihaela; Gupta, Neeraj; Hanley, Michael; Venkatakrishnan, Karthik; Wu, Jing-Tao; Xia, Cindy; Zhang, Xiaoquan; Chowdhury, Swapan.
Afiliación
  • Pusalkar S; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA. Sandeepraj.Pusalkar@takeda.com.
  • Plesescu M; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Gupta N; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Hanley M; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Venkatakrishnan K; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Wu JT; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Xia C; Alnylam Pharmaceuticals, 300 Third Street, Cambridge, MA, 02142, USA.
  • Zhang X; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Chowdhury S; Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc. (a wholly owned subsidiary of Takeda Pharmaceutical Company Limited), 40 Landsdowne Street, Cambridge, MA, 02139, USA.
Cancer Chemother Pharmacol ; 82(5): 803-814, 2018 11.
Article en En | MEDLINE | ID: mdl-30128949
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Boro / Heces / Glicina / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Cancer Chemother Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Boro / Heces / Glicina / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Cancer Chemother Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania