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The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Petyuk, Vladislav A; Chang, Rui; Ramirez-Restrepo, Manuel; Beckmann, Noam D; Henrion, Marc Y R; Piehowski, Paul D; Zhu, Kuixi; Wang, Sven; Clarke, Jennifer; Huentelman, Matthew J; Xie, Fang; Andreev, Victor; Engel, Anzhelika; Guettoche, Toumy; Navarro, Loida; De Jager, Philip; Schneider, Julie A; Morris, Christopher M; McKeith, Ian G; Perry, Robert H; Lovestone, Simon; Woltjer, Randall L; Beach, Thomas G; Sue, Lucia I; Serrano, Geidy E; Lieberman, Andrew P; Albin, Roger L; Ferrer, Isidre; Mash, Deborah C; Hulette, Christine M; Ervin, John F; Reiman, Eric M; Hardy, John A; Bennett, David A; Schadt, Eric; Smith, Richard D; Myers, Amanda J.
Afiliación
  • Petyuk VA; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA.
  • Chang R; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ramirez-Restrepo M; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Beckmann ND; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Henrion MYR; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Piehowski PD; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA.
  • Zhu K; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Wang S; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Clarke J; Food Science and Technology Department, University of Nebraska-Lincoln, Lincoln, NE, USA.
  • Huentelman MJ; Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Xie F; Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA.
  • Andreev V; Arbor Research Collaborative for Health, 340 E Huron St # 300, Ann Arbor, MI, USA.
  • Engel A; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Guettoche T; Roche Sequencing, 4300 Hacienda Drive, Pleasanton, CA, USA.
  • Navarro L; Roche Sequencing, 4300 Hacienda Drive, Pleasanton, CA, USA.
  • De Jager P; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
  • Schneider JA; New York Genome Center, New York NY, USA.
  • Morris CM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
  • McKeith IG; Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Perry RH; Newcastle Brain Tissue Resource, Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.
  • Lovestone S; NIHR Biomedical Research Centre, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.
  • Woltjer RL; Neuropathology and Cellular Pathology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK.
  • Beach TG; University of Oxford, Medical Sciences Division, Department of Psychiatry, Warneford Hospital, Oxford, UK.
  • Sue LI; Neuropathology Core of the Layton Aging and Alzheimer’s Disease Center, Oregon Health and Science University, Portland, OR, USA.
  • Serrano GE; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Lieberman AP; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Albin RL; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Ferrer I; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Mash DC; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
  • Hulette CM; Geriatrics Research, Education, and Clinical Center, VAAAHS, Ann Arbor, MI, USA.
  • Ervin JF; Department of Pathology and Experimental Therapeutics, University of Barcelona; CIBERNED; Hospitalet de Llobregat, Spain.
  • Reiman EM; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Hardy JA; Department of Pathology, Division of Neuropathology, Duke University Medical Center, Durham, NC, USA.
  • Bennett DA; Kathleen Price Bryan Brain Bank, Department of Medicine, Division of Neurology, Duke University, Durham, NC, USA.
  • Schadt E; The Arizona Alzheimer’s Consortium, Phoenix, Arizona, USA.
  • Smith RD; Banner Alzheimer’s Institute, Phoenix, Arizona, USA.
  • Myers AJ; Department of Molecular Neuroscience and Reta Lila Research Laboratories, University College London Institute of Neurology, London, UK.
Brain ; 141(9): 2721-2739, 2018 09 01.
Article en En | MEDLINE | ID: mdl-30137212

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas HSP70 de Choque Térmico / Enfermedad de Alzheimer Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Brain Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas HSP70 de Choque Térmico / Enfermedad de Alzheimer Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Brain Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido