Body Weight-Based Protocols During Whole Body FDG PET/CT Significantly Reduces Radiation Dose without Compromising Image Quality:Findings in a Large Cohort Study.
Acad Radiol
; 26(5): 658-663, 2019 05.
Article
en En
| MEDLINE
| ID: mdl-30145204
ABSTRACT
RATIONALE AND OBJECTIVES:
To investigate radiation dose reduction during whole body fluorodeoxyglucose (18F-FDG) positron emission tomographic (PET)/computed tomography (CT) by employing weight-based protocols. MATERIALS ANDMETHODS:
One thousand and twenty-eight patients were referred for 18F-FDG PET/CT study with one of two protocols conventional protocol I; 120 kVp, 120 mAs, 0.5 second rotation time, pitch 0.8 mm/rot across all body weights; four-tier body weight protocol II all used 140 kVp, 0.75 seconds rotation time and pitch 0.8 mm/rot Protocol A (≤60 kg) 35 mAs, Protocol B (61-80 kg) 50 mAs, Protocol C (81-100 kg) 65 mAs, and Protocol D (>101 kg) 100 mAs. All protocols employed tube current modulation. Quantitative and qualitative image visual grading characteristics assessed image quality.RESULTS:
Patient demographics demonstrated no significant difference between each protocol except for patient weight in weight protocol IIB (p < 0.009). Mean effective dose in all protocols were significantly lower in Protocol B compared to A (p < 0.009). Contrast-to-noise ratio demonstrated no differences between each protocol (p < 0.21) except for weight protocol in protocol IIA (<60 kg, pâ¯=â¯0.035) with the visual grading characteristics demonstrating preference over protocol II compared to I.CONCLUSION:
Significant reduction in radiation dose can be achieved using patient-specific body weight-based protocols during whole-body 18F-FDG PET/CT without compromising image quality when employing weight-based protocols.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peso Corporal
/
Exposición a la Radiación
/
Tomografía Computarizada por Tomografía de Emisión de Positrones
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Incidence_studies
/
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Límite:
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Acad Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Líbano