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Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2.
Hangas, Anu; Aasumets, Koit; Kekäläinen, Nina J; Paloheinä, Mika; Pohjoismäki, Jaakko L; Gerhold, Joachim M; Goffart, Steffi.
Afiliación
  • Hangas A; Department of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 111, FI-80101 Joensuu, Finland.
  • Aasumets K; Institute of Technology, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
  • Kekäläinen NJ; Department of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 111, FI-80101 Joensuu, Finland.
  • Paloheinä M; Department of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 111, FI-80101 Joensuu, Finland.
  • Pohjoismäki JL; Department of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 111, FI-80101 Joensuu, Finland.
  • Gerhold JM; Institute of Technology, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
  • Goffart S; Department of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 111, FI-80101 Joensuu, Finland.
Nucleic Acids Res ; 46(18): 9625-9636, 2018 10 12.
Article en En | MEDLINE | ID: mdl-30169847
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN Mitocondrial / Ciprofloxacina / ADN-Topoisomerasas de Tipo II / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2018 Tipo del documento: Article País de afiliación: Finlandia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN Mitocondrial / Ciprofloxacina / ADN-Topoisomerasas de Tipo II / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2018 Tipo del documento: Article País de afiliación: Finlandia