Can chronotype function as predictor of a persistent course of depressive and anxiety disorder?
J Affect Disord
; 242: 159-164, 2019 01 01.
Article
en En
| MEDLINE
| ID: mdl-30179789
ABSTRACT
BACKGROUND:
The role of chronotype, the individual timing of sleep/activity, has been studied in relation to depressive and anxiety disorders. A cross-sectional association between a depressive episode and evening-type has been identified. However, until now the predicting capacity of chronotype concerning persistence of psychiatric disorders remains unclear. Our aim is to examine whether a later chronotype in patients with a depressive and/or anxiety disorder can serve as a predictor of a persistent course.METHODS:
A subsample of patients with a depressive and/or anxiety disorder diagnosis and chronotype data of the longitudinal Netherlands Study of Depression and Anxiety (NESDA) was used. Diagnosis of depressive and anxiety disorders (1-month DSM-IV based diagnosis) were determined at baseline (nâ¯=â¯505). From this group persistence was determined at 2-year (FU2) (persistent course nâ¯=â¯248, non-persistent course nâ¯=â¯208) and 4-year follow-up (FU4) (persistent course nâ¯=â¯151, non-persistent course nâ¯=â¯264). Chronotype was assessed at baseline with the Munich Chronotype Questionnaire.RESULTS:
A later chronotype did not predict a persistent course of depressive and/or anxiety disorder at FU2 (OR (95% CI)â¯=â¯0.99 (0.83-1.19), Pâ¯=â¯0.92) or at FU4 (OR (95% CI)â¯=â¯0.94 (0.77-1.15), Pâ¯=â¯0.57).LIMITATIONS:
Persistence was defined as having a diagnosis of depressive and/or anxiety disorder at the two-year and four-year follow-up, patients may have remitted and relapsed between assessments.CONCLUSION:
Chronotype, measured as actual sleep timing, of patients with a depressive or anxiety disorder did not predict a persistent course which suggests it might be unsuitable as predictive tool in clinical settings.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastornos de Ansiedad
/
Ritmo Circadiano
/
Trastorno Depresivo
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Affect Disord
Año:
2019
Tipo del documento:
Article