The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth.

Chaaban, Sami; Jariwala, Shashank; Hsu, Chieh-Ting; Redemann, Stefanie; Kollman, Justin M; Müller-Reichert, Thomas; Sept, David; Bui, Khanh Huy; Brouhard, Gary J

The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth.

Chaaban, Sami; Jariwala, Shashank; Hsu, Chieh-Ting; Redemann, Stefanie; Kollman, Justin M; Müller-Reichert, Thomas; Sept, David; Bui, Khanh Huy; Brouhard, Gary J.

Afiliación

Chaaban S; Department of Biology, 1205 Avenue Docteur Penfield, Montréal, QC H3A 1B1, Canada.
Jariwala S; Department of Computational Medicine and Bioinformatics, 100 Washtenaw Avenue, Ann Arbor, MI 48109, USA.
Hsu CT; Department of Biology, 1205 Avenue Docteur Penfield, Montréal, QC H3A 1B1, Canada.
Redemann S; Experimental Center, Technische Universität Dresden, Faculty of Medicine, Fiedlerstraße 42, 01307 Dresden, Germany; Center for Membrane & Cell Physiology, University of Virginia and Department of Molecular Physiology & Biological Physics, 480 Ray C. Hung Drive, Charlottesville, VA 22903, USA
Kollman JM; Department of Biochemistry, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Müller-Reichert T; Experimental Center, Technische Universität Dresden, Faculty of Medicine, Fiedlerstraße 42, 01307 Dresden, Germany.
Sept D; Department of Biomedical Engineering, 2200 Bonisteel Boulevard, Ann Arbor, MI 48109, USA.
Bui KH; Department of Anatomy and Cell Biology, 3640 Rue University, Montréal, QC H3A 0C7, Canada.
Brouhard GJ; Department of Biology, 1205 Avenue Docteur Penfield, Montréal, QC H3A 1B1, Canada. Electronic address: gary.brouhard@mcgill.ca.

Dev Cell ; 47(2): 191-204.e8, 2018 10 22.

Article en En | MEDLINE | ID: mdl-30245157

Asunto(s)

Microtúbulos/fisiología; Tubulina (Proteína)/metabolismo; Tubulina (Proteína)/fisiología; Animales; Caenorhabditis elegans/metabolismo; Proteínas de Caenorhabditis elegans/fisiología; Guanosina Trifosfato; Microtúbulos/metabolismo; Microtúbulos/ultraestructura; Modelos Moleculares; Relación Estructura-Actividad

Palabras clave

C. elegans; catastrophe; cryo-EM; dynamic instability; microtubule; single molecule

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Microtúbulos Límite: Animals Idioma: En Revista: Dev Cell Asunto de la revista: EMBRIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

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