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Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
Reis, Joana; Cagide, Fernando; Valencia, Martín Estrada; Teixeira, José; Bagetta, Donatella; Pérez, Concepción; Uriarte, Eugenio; Oliveira, Paulo J; Ortuso, Francesco; Alcaro, Stefano; Rodríguez-Franco, María Isabel; Borges, Fernanda.
Afiliación
  • Reis J; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal.
  • Cagide F; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal.
  • Valencia ME; Instituto de Química Médica, (IQM-CSIC), C/Juan de la Cierva 3, 28006, Madrid, Spain.
  • Teixeira J; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal; CNC - Center for Neuroscience and Cell Biology, UC-Biotech, Biocant Park, University of Coimbra, Cantanhede, 3060-197, Portugal.
  • Bagetta D; Department of "Scienze della Salute", University "Magna Græcia" of Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Pérez C; Instituto de Química Médica, (IQM-CSIC), C/Juan de la Cierva 3, 28006, Madrid, Spain.
  • Uriarte E; Department of Organic Chemistry, Faculty of Pharmacy, Universidad of Santiago de Compostela, 15782, Santiago de Compostela, Spain; Applied Chemical Science Institute, Universidad Autonoma de Chile, 7500912, Santiago de Chile, Chile.
  • Oliveira PJ; CNC - Center for Neuroscience and Cell Biology, UC-Biotech, Biocant Park, University of Coimbra, Cantanhede, 3060-197, Portugal.
  • Ortuso F; Department of "Scienze della Salute", University "Magna Græcia" of Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Alcaro S; Department of "Scienze della Salute", University "Magna Græcia" of Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Rodríguez-Franco MI; Instituto de Química Médica, (IQM-CSIC), C/Juan de la Cierva 3, 28006, Madrid, Spain.
  • Borges F; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal. Electronic address: fborges@fc.up.pt.
Eur J Med Chem ; 158: 781-800, 2018 Oct 05.
Article en En | MEDLINE | ID: mdl-30245401
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Cromonas / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Cromonas / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Francia