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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
Vojinovic, Dina; Adams, Hieab H; Jian, Xueqiu; Yang, Qiong; Smith, Albert Vernon; Bis, Joshua C; Teumer, Alexander; Scholz, Markus; Armstrong, Nicola J; Hofer, Edith; Saba, Yasaman; Luciano, Michelle; Bernard, Manon; Trompet, Stella; Yang, Jingyun; Gillespie, Nathan A; van der Lee, Sven J; Neumann, Alexander; Ahmad, Shahzad; Andreassen, Ole A; Ames, David; Amin, Najaf; Arfanakis, Konstantinos; Bastin, Mark E; Becker, Diane M; Beiser, Alexa S; Beyer, Frauke; Brodaty, Henry; Bryan, R Nick; Bülow, Robin; Dale, Anders M; De Jager, Philip L; Deary, Ian J; DeCarli, Charles; Fleischman, Debra A; Gottesman, Rebecca F; van der Grond, Jeroen; Gudnason, Vilmundur; Harris, Tamara B; Homuth, Georg; Knopman, David S; Kwok, John B; Lewis, Cora E; Li, Shuo; Loeffler, Markus; Lopez, Oscar L; Maillard, Pauline; El Marroun, Hanan; Mather, Karen A; Mosley, Thomas H.
Afiliación
  • Vojinovic D; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands. d.vojinovic@erasmusmc.nl.
  • Adams HH; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands.
  • Jian X; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands.
  • Yang Q; The University of Texas Health Science Center at Houston Institute of Molecular Medicine, Houston, TX 77030, USA.
  • Smith AV; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA.
  • Bis JC; Icelandic Heart Association, Kopavogur 201, Iceland.
  • Teumer A; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.
  • Scholz M; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA.
  • Armstrong NJ; Institute for Community Medicine, University Medicine Greifswald, Greifswald 17475, Germany.
  • Hofer E; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig 04107, Germany.
  • Saba Y; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig 04103, Germany.
  • Luciano M; Mathematics and Statistics, Murdoch University, Perth, WA 6150, Australia.
  • Bernard M; Centre for Healthy Brain Ageing, School of Psychiatry, UNSW, Sydney, NSW 2052, Australia.
  • Trompet S; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz 8036, Austria.
  • Yang J; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz 8036, Austria.
  • Gillespie NA; Gottfried Schatz research center, Institute for Molecular biology and biochemistry, Graz 8010, Austria.
  • van der Lee SJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK.
  • Neumann A; Research Institute of the Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.
  • Ahmad S; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Andreassen OA; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Ames D; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.
  • Amin N; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
  • Arfanakis K; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23284, USA.
  • Bastin ME; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands.
  • Becker DM; Department of Child and Adolescent Psychiatry/ Psychology, Erasmus University Medical Center Rotterdam, Rotterdam 3000 CB, The Netherlands.
  • Beiser AS; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands.
  • Beyer F; Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo 0372, Norway.
  • Brodaty H; National Ageing Research Institute, Melbourne, VIC 3052, Australia.
  • Bryan RN; Academic Unit for Psychiatry of Old Age, University of Melbourne, Melbourne, VIC 3101, Australia.
  • Bülow R; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam 3015 CN, The Netherlands.
  • Dale AM; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.
  • De Jager PL; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
  • Deary IJ; Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
  • DeCarli C; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK.
  • Fleischman DA; Centre for Clinical Brain Sciences, University of Edinburgh & Brain Research Imaging Centre, University of Edinburgh, Edinburgh EH16 4SB, UK.
  • Gottesman RF; Division of Neuroimaging Sciences, Brain Research Imaging Centre, University of Edinburgh, Edinburgh EH16 4SB, UK.
  • van der Grond J; Division of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
  • Gudnason V; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA.
  • Harris TB; Department of Neurology, Max Planck Institute of Cognitive and Brain Sciences, Leipzig 04103, Germany.
  • Homuth G; Centre for Healthy Brain Ageing, School of Psychiatry, UNSW, Sydney, NSW 2052, Australia.
  • Knopman DS; Dementia Collaborative Research Centre - Assessment and Better Care, University of New South Wales, Sydney, NSW 2031, Australia.
  • Kwok JB; The University of Texas at Austin Dell Medical School, Austin, TX 78705, USA.
  • Lewis CE; Institute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald 17475, Germany.
  • Li S; Department of Cognitive Science, University of California, San Diego, La Jolla, CA 92093, USA.
  • Loeffler M; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA.
  • Lopez OL; Cell Circuits Program, Broad Institute, Cambridge, MA 02142, USA.
  • Maillard P; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK.
  • El Marroun H; Department of Neurology and Center for Neuroscience, University of California, Davis, CA 95817, USA.
  • Mather KA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.
  • Mosley TH; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Nat Commun ; 9(1): 3945, 2018 09 26.
Article en En | MEDLINE | ID: mdl-30258056
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma Humano / Ventrículos Laterales Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Aged / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma Humano / Ventrículos Laterales Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Aged / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido