New Insights into the Role of Trace Elements in IBD.
Biomed Res Int
; 2018: 1813047, 2018.
Article
en En
| MEDLINE
| ID: mdl-30258848
ABSTRACT
Micronutrient deficiencies are common in inflammatory bowel disease and have clinical impact, being both a sign of complicated disease and a cause of morbidity. The involved systemic inflammatory response is responsible for altering the concentration of a wide range of trace elements in the serum, including zinc and selenium. This review summarizes recent advances and evidence-based knowledge regarding the impact of selenium and zinc on oxidative stress and microbiota changes in IBD patients. Getting new insight into the impact of malnutrition, particularly on the micronutrients' impact on the development, composition, and metabolism of microbiota, as well as the influence of oxidative stress and the mucosal immune response, could help in implementing new management strategies for IBD patients, with focus on a more integrated approach.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligoelementos
/
Enfermedades Inflamatorias del Intestino
Límite:
Humans
Idioma:
En
Revista:
Biomed Res Int
Año:
2018
Tipo del documento:
Article
País de afiliación:
Rumanía