Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores.
Nat Commun
; 9(1): 4085, 2018 10 05.
Article
en En
| MEDLINE
| ID: mdl-30291230
ABSTRACT
Crucial steps in the miniaturisation of biosensors are the conversion of a biological signal into an electrical current as well as the direct sampling of bodily fluids. Here we show that protein sensors in combination with a nanopore, acting as an electrical transducer, can accurately quantify metabolites in real time directly from nanoliter amounts of blood and other bodily fluids. Incorporation of the nanopore into portable electronic devices will allow developing sensitive, continuous, and non-invasive sensors for metabolites for point-of-care and home diagnostics.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asparagina
/
Técnicas Biosensibles
/
Nanoporos
/
Glucosa
Tipo de estudio:
Evaluation_studies
Idioma:
En
Revista:
Nat Commun
Asunto de la revista:
BIOLOGIA
/
CIENCIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Países Bajos