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Targeting Cancer Cells and Tumor Microenvironment in Preclinical and Clinical Models of Hodgkin Lymphoma Using the Dual PI3Kδ/γ Inhibitor RP6530.
Locatelli, Silvia L; Careddu, Giuseppa; Serio, Simone; Consonni, Francesca M; Maeda, Akihiro; Viswanadha, Srikant; Vakkalanka, Swaroop; Castagna, Luca; Santoro, Armando; Allavena, Paola; Sica, Antonio; Carlo-Stella, Carmelo.
Afiliación
  • Locatelli SL; Department of Oncology and Hematology, Humanitas Cancer Center, Rozzano, Milan, Italy. carmelo.carlostella@hunimed.eu silvia.locatelli@cancercenter.humanitas.it.
  • Careddu G; Department of Oncology and Hematology, Humanitas Cancer Center, Rozzano, Milan, Italy.
  • Serio S; Department of Oncology and Hematology, Humanitas Cancer Center, Rozzano, Milan, Italy.
  • Consonni FM; Department of Inflammation and Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Maeda A; Department of Inflammation and Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Viswanadha S; Incozen Therapeutics, Hyderabad, India.
  • Vakkalanka S; Rhizen Pharmaceuticals S A, La Chaux-de-Fonds, Switzerland.
  • Castagna L; Department of Oncology and Hematology, Humanitas Cancer Center, Rozzano, Milan, Italy.
  • Santoro A; Department of Oncology and Hematology, Humanitas Cancer Center, Rozzano, Milan, Italy.
  • Allavena P; Department of Biomedical Sciences, Humanitas University, Rozzano, Milan, Italy.
  • Sica A; Department of Inflammation and Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Carlo-Stella C; Department of Biomedical Sciences, Humanitas University, Rozzano, Milan, Italy.
Clin Cancer Res ; 25(3): 1098-1112, 2019 02 01.
Article en En | MEDLINE | ID: mdl-30352904
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Benzopiranos / Enfermedad de Hodgkin / Fosfatidilinositol 3-Quinasas / Proliferación Celular / Microambiente Tumoral / Inhibidores de las Quinasa Fosfoinosítidos-3 Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Benzopiranos / Enfermedad de Hodgkin / Fosfatidilinositol 3-Quinasas / Proliferación Celular / Microambiente Tumoral / Inhibidores de las Quinasa Fosfoinosítidos-3 Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos